MATK Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2725549

Détail du produit

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MATK protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MATK (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Autre désignation: Matk (MATK Produits)

Synonymes: si:ch211-63j24.2 Protein, CHK Protein, CTK Protein, HHYLTK Protein, HYL Protein, HYLTK Protein, Lsk Protein, Ntk Protein, Batk Protein, megakaryocyte-associated tyrosine kinase Protein, zinc finger RNA binding protein 2 Protein, matk Protein, MATK Protein, Matk Protein, ZFR2 Protein

Sujet: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Poids moléculaire: 56.3 kDa

NCBI Accession: NP_647612