Menin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2725822

Détail du produit

Antigène: Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Menin protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Menin (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Autre désignation: Menin (MEN1 Produits)

Synonymes: MEAI Protein, SCG2 Protein, menin Protein, meai Protein, scg2 Protein, AW045611 Protein, menin 1 Protein, menin 1 L homeolog Protein, multiple endocrine neoplasia I Protein, multiple endocrine neoplasia 1 Protein, MEN1 Protein, men1 Protein, men1.L Protein, Men1 Protein

Sujet: This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 67.3 kDa

NCBI Accession: NP_570711

Pathways: Chromatin Binding, Positive Regulation of Endopeptidase Activity