MID1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2726004

Détail du produit

Antigène: MID1 (Midline 1 (MID1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MID1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Midline-1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MID1 (Midline 1 (MID1))

Autre désignation: Midline-1 (MID1 Produits)

Synonymes: BBBG1 Protein, FXY Protein, GBBB1 Protein, MIDIN Protein, OGS1 Protein, OS Protein, OSX Protein, RNF59 Protein, TRIM18 Protein, XPRF Protein, ZNFXY Protein, 61B3-R Protein, DXHXS1141 Protein, Fxy Protein, Trim18 Protein, Midline1 Protein, bbbg1 Protein, fxy Protein, gbbb1 Protein, midin Protein, ogs1 Protein, osx Protein, rnf59 Protein, trim18 Protein, xprf Protein, znfxy Protein, midline 1 Protein, midline 1 L homeolog Protein, MID1 Protein, Mid1 Protein, mid1 Protein, mid1.L Protein

Sujet: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the &aposRING-B box-coiled coil&apos (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.

Poids moléculaire: 75.1 kDa

NCBI Accession: NP_000372