MUS81 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2726587

Détail du produit

Antigène: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MUS81 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MUS81 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Autre désignation: Mus81 (MUS81 Produits)

Synonymes: CG3026 Protein, Dmel\\CG3026 Protein, EG:BACR7A4.16 Protein, MUS81 Protein, GB15332 Protein, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 Protein, ATMUS81 Protein, F6I18.220 Protein, F6I18_220 Protein, MMS AND UV SENSITIVE 81 Protein, SLX3 Protein, slx3 Protein, 1200008A18Rik Protein, AI182501 Protein, AW045863 Protein, wu:fc26g01 Protein, zgc:66489 Protein, zgc:91801 Protein, CG3026 gene product from transcript CG3026-RA Protein, MUS81 structure-specific endonuclease subunit Protein, crossover junction endonuclease MUS81 Protein, Restriction endonuclease, type II-like superfamily protein Protein, Mus81p Protein, Holliday junction resolvase subunit Mus81 Protein, MUS81 protein Protein, hypothetical protein Protein, mus81 Protein, MUS81 Protein, LOC725951 Protein, Mus81 Protein, CAALFM_C600540WA Protein

Sujet: This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after interstrand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.

Poids moléculaire: 61 kDa

NCBI Accession: NP_079404

Pathways: Réparation de l'ADN