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NACA Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

NACa1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2726835
  • Antigène Voir toutes NACA (NACa1) Protéines
    NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 3
    Origine
    • 4
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette NACA protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NACa1 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))
    Autre désignation
    Nascent Polypeptide-Associated Complex alpha Subunit (Naca) (NACa1 Produits)
    Synonymes
    AL022831 Protein, AL024382 Protein, Gm1878 Protein, mKIAA0363 Protein, skNAC Protein, ik:tdsubc_2b5 Protein, nkn Protein, tdsubc_2b5 Protein, xx:tdsubc_2b5 Protein, NACA1 Protein, nascent polypeptide-associated complex alpha polypeptide Protein, nascent polypeptide-associated complex alpha subunit Protein, Naca Protein, naca Protein, NACA Protein
    Sujet
    This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.
    Poids moléculaire
    23.2 kDa
    NCBI Accession
    NP_005585
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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