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NEDD4-2 Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)

NEDD4L Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2727064
  • Antigène Voir toutes NEDD4-2 (NEDD4L) Protéines
    NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant B
    Origine
    • 3
    • 1
    Humain
    Source
    • 2
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette NEDD4-2 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human NEDD4L (transcript variant b) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NEDD4L Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
    Autre désignation
    Nedd4l (NEDD4L Produits)
    Synonymes
    NEDD4-2 Protein, NEDD4.2 Protein, RSP5 Protein, hNEDD4-2 Protein, nedd4 Protein, nedd4-2 Protein, NEDD4 Protein, Nedd4-2 Protein, 1300012C07Rik Protein, Nedd4b Protein, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase Protein, NEDD4L Protein, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog Protein, neural precursor cell expressed, developmentally down-regulated gene 4-like Protein, NEDD4L Protein, LOC776799 Protein, nedd4l.S Protein, Nedd4l Protein
    Sujet
    This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
    Poids moléculaire
    98 kDa
    NCBI Accession
    NP_001138436
    Pathways
    Negative Regulation of Transporter Activity
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