NFYA Protein (His tag)

N° du produit ABIN2727237

Détail du produit

Antigène: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NFYA protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human NFYA (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Autre désignation: Nfya (NFYA Produits)

Synonymes: wu:fb16e03 Protein, ik:tdsubc_2b6 Protein, xx:tdsubc_2b6 Protein, NFYA Protein, CBF-A Protein, CBF-B Protein, HAP2 Protein, NF-YA Protein, AA407810 Protein, Cbf-b Protein, SEZ-10 Protein, SEZ10 Protein, nuclear transcription factor Y, alpha Protein, nuclear transcription factor Y subunit alpha Protein, nuclear transcription factor-Y alpha Protein, nfya Protein, NFYA Protein, Nfya Protein

Sujet: The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Poids moléculaire: 36.7 kDa

NCBI Accession: NP_002496

Pathways: Regulation of Lipid Metabolism by PPARalpha