NUDT5 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2727763

Détail du produit

Antigène: NUDT5 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 (NUDT5))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NUDT5 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human NUDT5 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NUDT5 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 (NUDT5))

Autre désignation: Nudt5 (NUDT5 Produits)

Synonymes: YSA1 Protein, YSA1H Protein, YSAH1 Protein, hYSAH1 Protein, NUDT5 Protein, wu:fe48a12 Protein, zgc:86930 Protein, nudix hydrolase 5 Protein, nudix hydrolase 5 L homeolog Protein, nudix (nucleoside diphosphate linked moiety X)-type motif 5 Protein, NUDT5 Protein, Nudt5 Protein, nudt5.L Protein, nudt5 Protein

Sujet: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.

Poids moléculaire: 24.1 kDa

NCBI Accession: NP_054861