Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)

Détails pour le produit réf. ABIN2727917
Nom de la protéine
Attributs du protein
Transcript Variant 2
4
1
1
1
1
Origine
Humain
3
2
1
1
1
Source
HEK-293 Cells
3
2
1
1
1
Type de proteíne
Recombinant
Purification/Conjugué
Myc-DYKDDDDK Tag
Application
Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
Options
Specificité Optimal preservation of protein structure, post-translational modifications and functions.
Attributs du produit
  • Recombinant human OPCML / OBCAM (transcript variant 2) protein expressed in HEK293 cells.
  • Produced with end-sequenced ORF clone
Pureté > 80 % as determined by SDS-PAGE and Coomassie blue staining
Nom de la protéine
Sujet This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Poids moléculaire 34.7 kDa
NCBI Accession NP_001012393
Indications d'application Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays
Commentaires

The tag is located at the C-terminal.

Restrictions For Research Use only
Concentration > 50 μg/mL
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Stock -80 °C
Stockage commentaire Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Images (Fournisseur)
Image no. 1 for Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) (ABIN2727917) Validation with Western Blot