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PCDHGB4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

PCDHGB4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2728397
  • Antigène Voir toutes PCDHGB4 Protéines
    PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 2
    Origine
    Humain
    Source
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PCDHGB4 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human PCDHGB4 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PCDHGB4 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PCDHGB4 (Protocadherin gamma Subfamily B, 4 (PCDHGB4))
    Autre désignation
    Pcdhgb4 (PCDHGB4 Produits)
    Synonymes
    CDH20 Protein, FIB2 Protein, PCDH-GAMMA-B4 Protein, protocadherin gamma subfamily B, 4 Protein, PCDHGB4 Protein, Pcdhgb4 Protein
    Sujet
    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes.
    Poids moléculaire
    84.2 kDa
    NCBI Accession
    NP_115269
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