PDE1B Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2728484

Détail du produit

Antigène: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PDE1B protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PDE1B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Autre désignation: Pde1b (PDE1B Produits)

Synonymes: 63kDa Protein, Pde1b1 Protein, PDE1B1 Protein, PDES1B Protein, Aop2 Protein, phosphodiesterase 1B, Ca2+-calmodulin dependent Protein, phosphodiesterase 1B Protein, Pde1b Protein, PDE1B Protein

Sujet: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Poids moléculaire: 61.2 kDa

NCBI Accession: NP_000915

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma