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PDIA3 Protein (His tag)

PDIA3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2728558
  • Antigène Voir toutes PDIA3 Protéines
    PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
    Type de proteíne
    Recombinant
    Origine
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PDIA3 protéine est marqué à la His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human PDIA3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    niveau d'endotoxine
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Top Product
    Discover our top product PDIA3 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Buffer
    Supplied as a 0.2 μM filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 7.5
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
    Autre désignation
    Pdia3 (PDIA3 Produits)
    Synonymes
    ER60 Protein, ERp57 Protein, ERp60 Protein, ERp61 Protein, GRP57 Protein, GRP58 Protein, HsT17083 Protein, P58 Protein, PI-PLC Protein, grp-58 Protein, 58kDa Protein, Erp Protein, Grp58 Protein, PDI Protein, PDI-Q2 Protein, PLC[a] Protein, Plca Protein, 1 Protein, 25D3-membrane-associated Protein, sb:cb825 Protein, erp57 Protein, grp58 Protein, pdia3 Protein, protein disulfide isomerase family A member 3 Protein, protein disulfide-isomerase A3 Protein, protein disulfide isomerase associated 3 Protein, protein disulfide isomerase family A, member 3 Protein, protein disulfide isomerase family A member 3 S homeolog Protein, PDIA3 Protein, Tsp_10062 Protein, Pdia3 Protein, pdia3 Protein, pdia3.S Protein
    Sujet
    This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.
    Poids moléculaire
    55.3kD
    NCBI Accession
    NP_005304
    Pathways
    Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
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