PHKA2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2728840

Détail du produit

Antigène: PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PHKA2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PHKA2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))

Autre désignation: Phka2 (PHKA2 Produits)

Synonymes: GSD9A Protein, PHK Protein, PYK Protein, PYKL Protein, XLG Protein, XLG2 Protein, PHKA2 Protein, 6330505C01Rik Protein, D330034O08 Protein, Phk Protein, phosphorylase kinase regulatory subunit alpha 2 Protein, phosphorylase kinase alpha 2 Protein, PHKA2 Protein, Phka2 Protein

Sujet: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010].

Poids moléculaire: 138.2 kDa

NCBI Accession: NP_000283

Pathways: Cellular Glucan Metabolic Process