PIK3 gamma Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2728968

Détail du produit

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PIK3 gamma protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PIK3CG protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Hashimoto, Tanaka, Takeda, Ito, Nagano et al.: "Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLC? and to Activate p44/42 MAPK in Human Aortic Endothelial ..." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0132835, (2015) (PubMed).

Détail du antigène

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Autre désignation: Pik3cg (PIK3CG Produits)

Synonymes: PI3CG Protein, PI3K Protein, PI3Kgamma Protein, PIK3 Protein, Pi3k Protein, wu:fb15d07 Protein, zgc:77033 Protein, pi3k Protein, 5830428L06Rik Protein, p110gamma Protein, p120-PI3K Protein, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Protein, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Protein, si:rp71-17i16.5 Protein, PIK3CG Protein, Pik3cg Protein, pik3cg Protein, si:rp71-17i16.5 Protein

Sujet: Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 126.3 kDa

NCBI Accession: NP_002640

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Inositol Metabolic Process, Hepatitis C, VEGF Signaling