PLA2G4A Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes PLA2G4A Protéines
- PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PLA2G4A protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human PLA2G4A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PLA2G4A Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
- Autre désignation
- Pla2g4a (PLA2G4A Produits)
- Synonymes
- PLA2G4 Protein, cPLA2-alpha Protein, Pla2c Protein, Pla2g4 Protein, cPLA2 Protein, pla2g4 Protein, CPLA2 Protein, PLA2G4A Protein, PLA2 Protein, PLA2G1B Protein, cPLA2alpha Protein, pla2g4a Protein, si:dkey-97o5.1 Protein, phospholipase A2 group IVA Protein, phospholipase A2 group IVA L homeolog Protein, phospholipase A2, group IVA (cytosolic, calcium-dependent) Protein, phospholipase A2, group IVAb (cytosolic, calcium-dependent) Protein, PLA2G4A Protein, Pla2g4a Protein, pla2g4a.L Protein, pla2g4ab Protein
- Sujet
- This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 85 kDa
- NCBI Accession
- NP_077734
- Pathways
- Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
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