BPIFA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2729200

Détail du produit

Antigène: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette BPIFA1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PLUNC (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Budding, van de Graaf, Hoefnagel, Hack, Otten: "Anti-BPIFA1/SPLUNC1: a new autoantibody prevalent in patients with endstage cystic fibrosis." dans: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, Vol. 13, Issue 3, pp. 281-8, (2014) (PubMed).

Détail du antigène

Antigène: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Autre désignation: Plunc (BPIFA1 Produits)

Synonymes: LUNX Protein, NASG Protein, PLUNC Protein, SPLUNC1 Protein, SPURT Protein, bA49G10.5 Protein, Plunc Protein, BPI fold containing family A member 1 Protein, BPI fold containing family A, member 1 Protein, BPIFA1 Protein, Bpifa1 Protein

Sujet: This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3&apos UTR have been detected, but the full-length nature of only three are known.

Poids moléculaire: 24.6 kDa

NCBI Accession: NP_057667