PPP1R12B Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

N° du produit ABIN2729470

Détail du produit

Antigène: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 4

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PPP1R12B protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PPP1R12B / MYPT2 (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Autre désignation: Ppp1r12b,mypt2 (PPP1R12B Produits)

Synonymes: 1810037O03Rik Protein, 9530009M10Rik Protein, AI132431 Protein, Mypt2 Protein, MYPT2 Protein, PP1bp55 Protein, protein phosphatase 1, regulatory subunit 12B Protein, protein phosphatase 1, regulatory (inhibitor) subunit 12B Protein, protein phosphatase 1 regulatory subunit 12B Protein, Ppp1r12b Protein, PPP1R12B Protein

Sujet: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.

Poids moléculaire: 26.1 kDa

NCBI Accession: NP_115287

Pathways: M Phase