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PPM1B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

PPM1B Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2729803
  • Antigène Voir toutes PPM1B Protéines
    PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 1
    Origine
    • 5
    • 1
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PPM1B protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Protein phosphatase 1B / PPM1B (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PPM1B Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
    Autre désignation
    Protein Phosphatase 1b,ppm1b (PPM1B Produits)
    Synonymes
    PP2C-beta-X Protein, PP2CB Protein, PP2CBETA Protein, PPC2BETAX Protein, Pp2c2 Protein, fc18g04 Protein, ppm1a Protein, wu:fc18g04 Protein, zgc:92329 Protein, pp2c-beta-x Protein, pp2cb Protein, pp2cbeta Protein, ppc2betax Protein, zgc:92031 Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B Protein, protein phosphatase 1B, magnesium dependent, beta isoform Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1B Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Bb Protein, protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Ba Protein, PPM1B Protein, Ppm1b Protein, ppm1bb Protein, ppm1b.L Protein, ppm1ba Protein
    Sujet
    The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
    Poids moléculaire
    52.5 kDa
    NCBI Accession
    NP_002697
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