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PPM1F Protein (Myc-DYKDDDDK Tag)

PPM1F Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2729807
  • Antigène Voir toutes PPM1F Protéines
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    Type de proteíne
    Recombinant
    Origine
    • 3
    • 1
    • 1
    Humain
    Source
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PPM1F protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Protein phosphatase 1F / PPM1F protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PPM1F Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    Autre désignation
    Protein Phosphatase 1f,ppm1f (PPM1F Produits)
    Synonymes
    1110021B16Rik Protein, 4933427B07Rik Protein, CaMKPase Protein, Popx2 Protein, mKIAA0015 Protein, CAMKP Protein, FEM-2 Protein, POPX2 Protein, hFEM-2 Protein, protein phosphatase, Mg2+/Mn2+ dependent 1F Protein, protein phosphatase 1F (PP2C domain containing) Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1F Protein, PPM1F Protein, Ppm1f Protein
    Sujet
    The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.
    Poids moléculaire
    49.7 kDa
    NCBI Accession
    NP_055449
    Pathways
    Positive Regulation of Endopeptidase Activity
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