PPM1L Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2729816

Détail du produit

Antigène: PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PPM1L protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Protein phosphatase 1L / PPM1L protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))

Autre désignation: Protein Phosphatase 1l,ppm1l (PPM1L Produits)

Synonymes: 3222401G13 Protein, 5930404J21Rik Protein, AI481720 Protein, AW045850 Protein, PP2C Protein, PP2Cepsilon Protein, Pp2ce Protein, Ppp2ce Protein, mKIAA4175 Protein, PP2C-epsilon Protein, PP2CE Protein, PPM1-LIKE Protein, ppm1l Protein, zgc:153235 Protein, zgc:154091 Protein, protein phosphatase 1 (formerly 2C)-like Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1L Protein, protein phosphatase, Mg2+/Mn2+ dependent 1L Protein, protein phosphatase, Mg2+/Mn2+ dependent 1L L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Lb Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1La Protein, Ppm1l Protein, PPM1L Protein, ppm1l.L Protein, ppm1lb Protein, ppm1la Protein

Sujet: The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 40.9 kDa

NCBI Accession: NP_640338