PTGER4 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2730063

Détail du produit

Antigène: PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PTGER4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PTGER4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))

Autre désignation: Ptger4 (PTGER4 Produits)

Synonymes: EP4 Protein, PGE2R-EP4 Protein, ptger4 Protein, ptger4l Protein, PTGER4 Protein, EP4R Protein, Ptgerep4 Protein, Ptger Protein, ep4 Protein, prostaglandin E receptor 4 Protein, prostaglandin E receptor 4 (subtype EP4) Protein, prostaglandin E receptor 4 (subtype EP4) a Protein, prostaglandin E receptor 4 subtype EP4 Protein, PTGER4 Protein, ptger4a Protein, ptger4 Protein, Ptger4 Protein

Sujet: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.

Poids moléculaire: 52.9 kDa

NCBI Accession: NP_000949