PTPRK Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes PTPRK Protéines
- PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PTPRK protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human PTPRK (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTPRK Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))
- Autre désignation
- Ptprk (PTPRK Produits)
- Synonymes
- R-PTP-kappa Protein, Rptpk Protein, AI853699 Protein, PTPk Protein, RPTPkappa Protein, protein tyrosine phosphatase, receptor type K Protein, protein tyrosine phosphatase, receptor type, K Protein, PTPRK Protein, Ptprk Protein
- Sujet
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.
- Poids moléculaire
- 160.3 kDa
- NCBI Accession
- NP_001129120
- Pathways
- Cell-Cell Junction Organization
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