PTPRO Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730148

Détail du produit

Antigène: PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PTPRO protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human PTPRO (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))

Autre désignation: Ptpro (PTPRO Produits)

Synonymes: GLEPP1 Protein, RPTP-BK Protein, D28 Protein, PTPBK Protein, PTPROt Protein, PTPU2 Protein, PTPoc Protein, PTPphi Protein, Ptpn15 Protein, R-PTP-O Protein, NPHS6 Protein, PTP-OC Protein, PTP-U2 Protein, PTPROT Protein, protein tyrosine phosphatase, receptor type O Protein, protein tyrosine phosphatase, receptor type, O Protein, PTPRO Protein, Ptpro Protein

Sujet: This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.

Poids moléculaire: 47 kDa

NCBI Accession: NP_109594

Pathways: Cell-Cell Junction Organization