RAD23B Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes RAD23B Protéines
- RAD23B (RAD23 Homolog B (RAD23B))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette RAD23B protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human RAD23B protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RAD23B Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- RAD23B (RAD23 Homolog B (RAD23B))
- Autre désignation
- Rad23b (RAD23B Produits)
- Synonymes
- HHR23B Protein, HR23B Protein, P58 Protein, 0610007D13Rik Protein, AV001138 Protein, mHR23B Protein, p58 Protein, MGC107846 Protein, zgc:65951 Protein, RAD23 homolog B, nucleotide excision repair protein Protein, UV excision repair protein RAD23 homolog B Protein, RAD23 homolog B, nucleotide excision repair protein S homeolog Protein, RAD23B Protein, Rad23b Protein, rd23b Protein, rad23b Protein, rad23b.S Protein
- Sujet
- The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Poids moléculaire
- 43 kDa
- NCBI Accession
- NP_002865
- Pathways
- Réparation de l'ADN
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