RAD9A Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2730420

Détail du produit

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RAD9A protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RAD9A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Autre désignation: Rad9a (RAD9A Produits)

Synonymes: RAD9 Protein, Rad9 Protein, rad9a Protein, MGC89062 Protein, XRad9 Protein, rad9 Protein, RAD9 checkpoint clamp component A Protein, RAD9 checkpoint clamp component B Protein, RAD9 checkpoint clamp component A L homeolog Protein, RAD9A Protein, Rad9a Protein, rad9a Protein, rad9b Protein, rad9a.L Protein

Sujet: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 42.4 kDa

NCBI Accession: NP_004575

Pathways: Positive Regulation of Response to DNA Damage Stimulus