RASGRP2 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730540

Détail du produit

Antigène: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 4

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RASGRP2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RASGRP2 (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Autre désignation: Rasgrp2 (RASGRP2 Produits)

Synonymes: CALDAG-GEFI Protein, CDC25L Protein, xrasgrp2 Protein, RASGRP2 Protein, Caldaggef1 Protein, CalDAG-GEFI Protein, rasgrp2 Protein, RAS guanyl releasing protein 2 Protein, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog Protein, RAS, guanyl releasing protein 2 Protein, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog Protein, RASGRP2 Protein, rasgrp2.S Protein, Rasgrp2 Protein, rasgrp2.L Protein

Sujet: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 69.1 kDa

NCBI Accession: NP_001092141

Pathways: TCR Signaling