SEC24D Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2731577

Détail du produit

Antigène: SEC24D (SEC24 Family, Member D (S. Cerevisiae) (SEC24D))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SEC24D protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SEC24D protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SEC24D (SEC24 Family, Member D (S. Cerevisiae) (SEC24D))

Autre désignation: Sec24d (SEC24D Produits)

Synonymes: Gm1349 Protein, 2310020L09Rik Protein, sec24d Protein, SEC24 homolog D, COPII coat complex component Protein, Sec24 related gene family, member D (S. cerevisiae) Protein, SEC24 homolog D, COPII coat complex component S homeolog Protein, SEC24D Protein, Sec24d Protein, sec24d.S Protein

Sujet: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 112.8 kDa

NCBI Accession: NP_055637