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SEC31A Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

SEC31A Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2731578
  • Antigène Voir toutes SEC31A Protéines
    SEC31A (SEC31 Homolog A (SEC31A))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 3
    Origine
    • 2
    • 1
    Humain
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette SEC31A protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human SEC31A (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SEC31A Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    SEC31A (SEC31 Homolog A (SEC31A))
    Autre désignation
    Sec31a (SEC31A Produits)
    Synonymes
    ABP125 Protein, ABP130 Protein, HSPC334 Protein, SEC31L1 Protein, Sec31l1 Protein, VAP1 Protein, 1810024J13Rik Protein, AU042160 Protein, HSPC275 Protein, cb354 Protein, sec31p Protein, zgc:63547 Protein, SEC31 homolog A, COPII coat complex component Protein, Sec31 homolog A (S. cerevisiae) Protein, SEC31A Protein, Sec31a Protein, sec31a Protein
    Sujet
    The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Poids moléculaire
    131.4 kDa
    NCBI Accession
    NP_001070676
    Pathways
    ER-Nucleus Signaling
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