BSCL2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2731605

Détail du produit

Antigène: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette BSCL2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Seipin / BSCL2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Autre désignation: Seipin,bscl2 (BSCL2 Produits)

Synonymes: GNG3LG Protein, HMN5 Protein, SPG17 Protein, 2900097C17Rik Protein, AI046355 Protein, Gng3lg Protein, BSCL2, seipin lipid droplet biogenesis associated Protein, Berardinelli-Seip congenital lipodystrophy 2 (seipin) Protein, BSCL2 Protein, Bscl2 Protein

Sujet: This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by RefSeq, Mar 2011].

Poids moléculaire: 44.2 kDa

NCBI Accession: NP_116056