SKAP2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732105

Détail du produit

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SKAP2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SKAP2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Autre désignation: Skap2 (SKAP2 Produits)

Synonymes: scap2 Protein, 2610021A10Rik Protein, AA960083 Protein, BB137539 Protein, RA70 Protein, SKAP-HOM Protein, Saps Protein, Scap2 Protein, mSKAP55R Protein, PRAP Protein, SAPS Protein, SCAP2 Protein, SKAP55R Protein, Scap55r Protein, SKAP55 Protein, si:dz227h09.6 Protein, si:dz31b14.4 Protein, zgc:158223 Protein, zgc:65975 Protein, src kinase associated phosphoprotein 2 L homeolog Protein, SRC kinase associated phosphoprotein 2 Protein, src family associated phosphoprotein 2 Protein, src kinase associated phosphoprotein 2 Protein, skap2.L Protein, CCC13826_0176 Protein, Skap2 Protein, SKAP2 Protein, skap2 Protein

Sujet: The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 41 kDa

NCBI Accession: NP_003921