SLC6A4 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732177

Détail du produit

Antigène: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SLC6A4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SLC6A4 / SERT protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Savy, Fitchett, McQuade, Gartside, Morris, Blain, Judge: "Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour." dans: Neurotoxicology, Vol. 50, pp. 149-56, (2015) (PubMed).

Détail du antigène

Antigène: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Autre désignation: Slc6a4,sert (SLC6A4 Produits)

Synonymes: 5-HTT Protein, 5-HTTLPR Protein, 5HTT Protein, HTT Protein, OCD1 Protein, SERT Protein, SERT1 Protein, hSERT Protein, AI323329 Protein, Htt Protein, Sert Protein, CG4545 Protein, DmSERT Protein, DmSerT Protein, Dmel\\CG4545 Protein, dSERT Protein, dSERT1 Protein, dSerT Protein, dSert Protein, dsert Protein, SLC6A4 Protein, solute carrier family 6 member 4 Protein, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 Protein, Serotonin transporter Protein, huntingtin Protein, solute carrier family 6 (neurotransmitter transporter), member 4b Protein, solute carrier family 6 (neurotransmitter transporter), member 4a Protein, SLC6A4 Protein, Slc6a4 Protein, SerT Protein, LOC100540532 Protein, slc6a4 Protein, slc6a4b Protein, slc6a4a Protein

Sujet: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Poids moléculaire: 70.1 kDa

NCBI Accession: NP_001036