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SNRPN Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

SNRPN Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2732320
  • Antigène Voir toutes SNRPN Protéines
    SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 2
    Origine
    • 4
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette SNRPN protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human snRNP-N / Sm-N (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SNRPN Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
    Autre désignation
    Snrnp-N,sm-N (SNRPN Produits)
    Synonymes
    SNRB' Protein, SNRPB' Protein, Snrpn Protein, zgc:77315 Protein, HCERN3 Protein, PWCR Protein, RT-LI Protein, SM-D Protein, SMN Protein, SNRNP-N Protein, SNURF-SNRPN Protein, sm-N Protein, 2410045I01Rik Protein, Peg4 Protein, Pwcr1 Protein, FE 294 Protein, FE 294 psi Protein, FE294 Protein, FE294 psi Protein, SNURF Protein, SNRPN Protein, QflA-11237 Protein, QtrA-10022 Protein, Sm-N Protein, SmN Protein, snRNP-N Protein, small nuclear ribonucleoprotein polypeptide-like Protein, small nuclear ribonucleoprotein polypeptides B and B1 Protein, small nuclear ribonucleoprotein polypeptide N Protein, small nuclear ribonucleoprotein N Protein, small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 Protein, SNRPN upstream reading frame Protein, Small nuclear ribonucleoprotein-associated protein N Protein, SNRPL Protein, snrpb Protein, SNRPN Protein, Snrpn Protein, snrpn Protein, SNURF Protein
    Sujet
    The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.
    Poids moléculaire
    24.4 kDa
    NCBI Accession
    NP_073716
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