SNX15 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

N° du produit ABIN2732393

Détail du produit

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant A

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SNX15 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Sorting nexin-15 (SNX15) (transcript variant A) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Autre désignation: Sorting Nexin-15 (Snx15) (SNX15 Produits)

Synonymes: SNX15 Protein, hsaf001435 Protein, snx15 Protein, MGC154249 Protein, HSAF001435 Protein, 1500032B08Rik Protein, E130013C21Rik Protein, sorting nexin 15 Protein, sorting nexin 15 S homeolog Protein, SNX15 Protein, snx15.S Protein, snx15 Protein, Snx15 Protein

Sujet: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Poids moléculaire: 38.1 kDa

NCBI Accession: NP_037438