SOX2 Protein (Myc-DYKDDDDK Tag)
-
- Antigène Voir toutes SOX2 Protéines
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SOX2 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
-
- Recombinant human SOX2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SOX2 Protéine
-
-
- Indications d'application
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming." dans: Cell, Vol. 161, Issue 3, pp. 555-68, (2015) (PubMed).
: "
-
Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming." dans: Cell, Vol. 161, Issue 3, pp. 555-68, (2015) (PubMed).
-
- Antigène
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- Autre désignation
- Sox2 (SOX2 Produits)
- Synonymes
- ANOP3 Protein, MCOPS3 Protein, RGD1565646 Protein, Sox-2 Protein, lcc Protein, ysb Protein, cb236 Protein, wu:fb83g04 Protein, wu:fc14d07 Protein, zgc:65860 Protein, zgc:77389 Protein, SRY-box2 Protein, Xsox-2 Protein, anop3 Protein, mcops3 Protein, sox-2 Protein, SRY-box 2 Protein, SRY box 2 Protein, SRY (sex determining region Y)-box 2 Protein, SRY-box 2 S homeolog Protein, SOX2 Protein, Sox2 Protein, sox2 Protein, sox2.S Protein
- Sujet
- This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
- Poids moléculaire
- 34.1 kDa
- NCBI Accession
- NP_003097
- Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
-