SOX4 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732454

Détail du produit

Antigène: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SOX4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SOX4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Kato, Bhattaram, Penzo-Méndez, Gadi, Lefebvre: "SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 30, Issue 9, pp. 1560-71, (2015) (PubMed).

Détail du antigène

Antigène: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Autre désignation: Sox4 (SOX4 Produits)

Synonymes: EVI16 Protein, AA682046 Protein, Sox-4 Protein, sox4 Protein, wu:fb82f08 Protein, wu:fq41g10 Protein, zgc:65850 Protein, zgc:77392 Protein, SRY-box 4 Protein, SRY box 4 Protein, SRY (sex determining region Y)-box 4 Protein, SRY (sex determining region Y)-box 4a Protein, SOX4 Protein, Sox4 Protein, sox4a Protein

Sujet: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Poids moléculaire: 47.1 kDa

NCBI Accession: NP_003098