SPG20 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2732510

Détail du produit

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SPG20 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Spartin / SPG20 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Autre désignation: Spartin,spg20 (SPG20 Produits)

Synonymes: SPARTIN Protein, TAHCCP1 Protein, AI840044 Protein, C79168 Protein, mKIAA0610 Protein, spartin Protein, Spg20 Protein, spg20a Protein, zgc:172059 Protein, spg20b Protein, zgc:153766 Protein, spartin Protein, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) Protein, spartin a Protein, spartin b Protein, SPART Protein, Spg20 Protein, Spart Protein, sparta Protein, spartb Protein

Sujet: This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).

Poids moléculaire: 72.7 kDa

NCBI Accession: NP_001135768

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interactome