SPDEF/PSE Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732544

Détail du produit

Antigène: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SPDEF/PSE protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human SPDEF protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Autre désignation: Spdef (SPDEF Produits)

Synonymes: PDEF Protein, RP11-375E1__A.3 Protein, bA375E1.3 Protein, pdef Protein, Pse Protein, SAM pointed domain containing ETS transcription factor Protein, SAM pointed domain containing ets transcription factor Protein, SPDEF Protein, Spdef Protein

Sujet: The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 37.3 kDa

NCBI Accession: NP_036523