SPRY2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732614

Détail du produit

Antigène: SPRY2 (Sprouty Homolog 2 (SPRY2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SPRY2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Sprouty homolog 2 / SPRY2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: SPRY2 (Sprouty Homolog 2 (SPRY2))

Autre désignation: Sprouty Homolog 2,spry2 (SPRY2 Produits)

Synonymes: wu:fk66h11 Protein, wu:fk93e11 Protein, zgc:110440 Protein, hspry2 Protein, xspry2 Protein, sprouty2 Protein, Xsprouty2 Protein, sprouty-2 Protein, Xtsprouty2 Protein, hSPRY2 Protein, sprouty RTK signaling antagonist 2 Protein, sprouty RTK signaling antagonist 2 S homeolog Protein, sprouty homolog 2 (Drosophila) Protein, spry2 Protein, SPRY2 Protein, spry2.S Protein, Spry2 Protein

Sujet: This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.

Poids moléculaire: 34.5 kDa

NCBI Accession: NP_005833

Pathways: EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation