STARD4 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2732765

Détail du produit

Antigène: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette STARD4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human STARD4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Autre désignation: Stard4 (STARD4 Produits)

Synonymes: 4632419C16Rik Protein, 9030213J02Rik Protein, AA517649 Protein, AW324468 Protein, StAR related lipid transfer domain containing 4 Protein, StAR-related lipid transfer (START) domain containing 4 Protein, STARD4 Protein, Stard4 Protein

Sujet: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1 MIM 184756) and by liver X receptors (e.g., LXRA MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008].

Poids moléculaire: 23.3 kDa

NCBI Accession: NP_631903