TAX1BP3 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2733250

Détail du produit

Antigène: TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TAX1BP3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TAX1BP3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TAX1BP3 (Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))

Autre désignation: Tax1bp3 (TAX1BP3 Produits)

Synonymes: TIP-1 Protein, 1300011C24Rik Protein, RP23-263M10.10 Protein, tax1bp3 Protein, wu:fb37e03 Protein, wu:fc23g08 Protein, zgc:55513 Protein, Tax1 binding protein 3 Protein, Tax1 (human T cell leukemia virus type I) binding protein 3 Protein, Tax1 (human T-cell leukemia virus type I) binding protein 3 S homeolog Protein, Tax1 (human T-cell leukemia virus type I) binding protein 3 Protein, TAX1BP3 Protein, Tax1bp3 Protein, tax1bp3.S Protein, tax1bp3 Protein

Sujet: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 13.6 kDa

NCBI Accession: NP_055419

Pathways: Monocarboxylic Acid Catabolic Process