TJP3 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2733730

Détail du produit

Antigène: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TJP3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Tight junction protein 3 (zona occludens 3) (TJP3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Abstract: TJP3 Produits

Synonymes: cb766 Protein, wu:fj93c08 Protein, zo-3 Protein, zo3 Protein, ZO-3 Protein, ZO3 Protein, tight junction protein 3 Protein, tight junction protein 3 S homeolog Protein, tjp3 Protein, tjp3.S Protein, TJP3 Protein, Tjp3 Protein

Sujet: The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1.

Poids moléculaire: 104.6 kDa

NCBI Accession: NP_055243