NTRK3 Protein (DYKDDDDK Tag)

N° du produit ABIN2734344

Détail du produit

Antigène: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Type de proteíne: Recombinant

Origine: Humain

Source: Insect cells (Sf9)

Purification/Conjugué: Cette NTRK3 protéine est marqué à la DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TrkC (C-term DDK tag) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Autre désignation: Trkc (NTRK3 Produits)

Synonymes: TRKC Protein, gp145(trkC) Protein, trkC Protein, AW125844 Protein, Ntrk3_tv3 Protein, TrkC Protein, neurotrophic receptor tyrosine kinase 3 Protein, neurotrophic tyrosine kinase, receptor, type 3 Protein, NTRK3 Protein, Ntrk3 Protein

Sujet: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 44.7 kDa

NCBI Accession: NP_001012338

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, Regulation of Cell Size