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Vitamin D Receptor Protein (VDR) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

VDR Origine: Chemical Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2735369
  • Antigène Voir toutes Vitamin D Receptor (VDR) Protéines
    Vitamin D Receptor (VDR)
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 1
    Origine
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Chemical
    Source
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Vitamin D Receptor protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Vitamin D3 receptor / NR1I1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product VDR Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    Vitamin D Receptor (VDR)
    Autre désignation
    Vitamin d3 Receptor,nr1i1 (VDR Produits)
    Synonymes
    vdrbeta Protein, vdr0 Protein, LOC100136219 Protein, NR1I1-B Protein, gb:dq017633 Protein, vdr-b Protein, Ci-VDR-b Protein, VDR Protein, LOC100221284 Protein, vdr-A Protein, xVDR Protein, Nr1i1 Protein, vdr Protein, NR1I1 Protein, PPP1R163 Protein, vitamin D (1,25- dihydroxyvitamin D3) receptor Protein, vitamin D receptor Protein, vitamin D3 receptor A Protein, vitamin D receptor b Protein, nuclear receptor VDR-b Protein, vitamin D (1,25- dihydroxyvitamin D3) receptor L homeolog Protein, vitamin D (1,25-dihydroxyvitamin D3) receptor Protein, vitamin D receptor a Protein, vdr Protein, vdr0 Protein, VDR Protein, LOC100136219 Protein, vdrb Protein, vdr-b Protein, vdr.L Protein, Vdr Protein, vdra Protein
    Classe de substances
    Chemical
    Sujet
    This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.
    Poids moléculaire
    48.1 kDa
    NCBI Accession
    NP_000367
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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