WDR73 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2735532

Détail du produit

Antigène: WDR73 (WD Repeat Domain 73 (WDR73))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette WDR73 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human WDR73 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: WDR73 (WD Repeat Domain 73 (WDR73))

Autre désignation: Wdr73 (WDR73 Produits)

Synonymes: 1200011I23Rik Protein, 2410008B13Rik Protein, AI848574 Protein, C85352 Protein, zgc:112071 Protein, WD repeat domain 73 Protein, WD repeat domain 73 L homeolog Protein, WDR73 Protein, Wdr73 Protein, wdr73.L Protein, wdr73 Protein

Sujet: The protein encoded by this gene is thought to contain multiple WD40 repeats. WD40 repeats are motifs that contain 40-60 amino acids, and usually end with Trp-Asp (WD). This protein is found in the cytoplasm during interphase, but accumulates at the spindle poles and astral microtubules during mitosis. Reduced expression of this gene results in abnormalities in the size and morphology of the nucleus. Mutations in this gene have been associated with Galloway-Mowat syndrome PMID: 25466283), which is a rare autosomal recessive disorder that affects both the central nervous system and kidneys. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 41.5 kDa

NCBI Accession: NP_116245