WWOX Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2735647

Détail du produit

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette WWOX protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human WWOX / FOR (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Autre désignation: Wwox,for (WWOX Produits)

Synonymes: CG7221 Protein, DmWWOX Protein, Dmel\\CG7221 Protein, anon-EST:Posey177 Protein, GB11795 Protein, WWOX Protein, D16S432E Protein, FOR Protein, FRA16D Protein, HHCMA56 Protein, PRO0128 Protein, SDR41C1 Protein, WOX1 Protein, zgc:55975 Protein, 5330426P09Rik Protein, 9030416C10Rik Protein, WW domain containing oxidoreductase Protein, WW domain-containing oxidoreductase Protein, Wwox Protein, LOC411815 Protein, WWOX Protein, CpipJ_CPIJ004939 Protein, MCYG_01584 Protein, VDBG_05631 Protein, VDBG_01326 Protein, VDBG_06753 Protein, Tsp_03967 Protein, LOC100284583 Protein, wwox Protein

Sujet: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 46.5 kDa

NCBI Accession: NP_057457