YAP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2735709

Détail du produit

Antigène: YAP1 (Yes-Associated Protein 1 (YAP1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette YAP1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human YAP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: YAP1 (Yes-Associated Protein 1 (YAP1))

Autre désignation: Yap1 (YAP1 Produits)

Synonymes: YAP Protein, YAP2 Protein, YAP65 Protein, YKI Protein, xyap Protein, yap Protein, yap2 Protein, yap65 Protein, yki Protein, AI325207 Protein, Yap Protein, Yap65 Protein, Yki Protein, Yorkie Protein, cb194 Protein, sb:cb194 Protein, si:ch211-181p1.5 Protein, si:dkey-3b8.3 Protein, wu:fc18c04 Protein, zgc:158380 Protein, Yes associated protein 1 Protein, Yes associated protein 1 S homeolog Protein, yes-associated protein 1 Protein, Yes-associated protein 1 Protein, YAP1 Protein, yap1.S Protein, Yap1 Protein, yap1 Protein

Sujet: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 54.3 kDa

NCBI Accession: NP_001123617

Pathways: Signalisation MAPK, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha