ZAP70 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2735753

Détail du produit

Antigène: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ZAP70 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ZAP70 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Autre désignation: Zap70 (ZAP70 Produits)

Synonymes: SRK Protein, STCD Protein, STD Protein, TZK Protein, ZAP-70 Protein, 70kDa Protein, AI327364 Protein, Srk Protein, mrtle Protein, mur Protein, zap70 Protein, MGC80670 Protein, MGC88962 Protein, ZAP70 Protein, zgc:110383 Protein, zeta chain of T-cell receptor associated protein kinase 70 Protein, putative tyrosine-protein kinase zap-70 Protein, zeta-chain (TCR) associated protein kinase Protein, zeta chain of T cell receptor associated protein kinase 70 Protein, zeta-chain (TCR) associated protein kinase 70kDa Protein, zeta chain of T cell receptor associated protein kinase 70kDa L homeolog Protein, zeta chain of T cell receptor associated protein kinase 70kDa Protein, tyrosine-protein kinase ZAP-70 Protein, ZAP70 Protein, Smp_149470 Protein, Zap70 Protein, zap70.L Protein, zap70 Protein, LOC707555 Protein, LOC100342021 Protein, LOC100390922 Protein, LOC100542877 Protein

Sujet: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Poids moléculaire: 69.7 kDa

NCBI Accession: NP_001070

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway