Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

PATZ1 Protein (His tag)

ZNF278 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2735982
  • Antigène Voir toutes PATZ1 (ZNF278) Protéines
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    Type de proteíne
    Recombinant
    Origine
    Humain
    Source
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PATZ1 protéine est marqué à la His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human ZNF278 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ZNF278 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    Autre désignation
    Znf278 (ZNF278 Produits)
    Synonymes
    ZNF278 Protein, MAZR Protein, PATZ Protein, RIAZ Protein, ZBTB19 Protein, ZSG Protein, dJ400N23 Protein, 8430401L15Rik Protein, AI447519 Protein, Mazr Protein, Patz Protein, Zfp278 Protein, Znf278 Protein, POZ/BTB and AT hook containing zinc finger 1 Protein, POZ/BTB and AT hook containing zinc finger 1 S homeolog Protein, POZ (BTB) and AT hook containing zinc finger 1 Protein, POZ-, AT hook-, and zinc finger-containing protein 1 Protein, PATZ1 Protein, patz1.S Protein, Patz1 Protein, LOC100153931 Protein
    Sujet
    The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(122)(p36.1q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.
    Poids moléculaire
    73.9 kDa
    NCBI Accession
    NP_055138
Vous êtes ici:
Support technique