KAT2A Protein (His tag)

N° du produit ABIN2745695

Détail du produit

Antigène: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Insect cells (Sf21)

Purification/Conjugué: Cette KAT2A protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Réactivité croisée: Humain

Attributs du produit: Human GCN5 is fused to a His-tag.

Pureté: >95 % (SDS-PAGE)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

~200-300ng are required for standard HAT assay.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride, 0.2 % NP-40, 50 mM imidazole and 10 % glycerol.

Stock: -20 °C,-80 °C

Stockage commentaire: Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C.

Date de péremption: 6 months

Détail du antigène

Antigène: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Autre désignation: GCN5 (KAT2A Produits)

Synonymes: KAT2A Protein, GCN5L2 Protein, GCN5 Protein, PCAF-b Protein, hGCN5 Protein, 1110051E14Rik Protein, AW212720 Protein, Gcn5 Protein, Gcn5l2 Protein, mmGCN5 Protein, K(lysine) acetyltransferase 2A Protein, lysine acetyltransferase 2A Protein, histone acetyltransferase KAT2A Protein, ras-related protein Rab-5C Protein, KAT2A Protein, LOC100176452 Protein, LOC100597293 Protein, Kat2a Protein

Sujet: GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation