JAG2 Protein (AA 1-1054) (Fc Tag)
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- Antigène Voir toutes JAG2 Protéines
- JAG2 (Jagged 2 (JAG2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-1054
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette JAG2 protéine est marqué à la Fc Tag.
- Application
- SDS-PAGE (SDS)
- Réactivité croisée
- Humain
- Attributs du produit
- Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
- Pureté
- >90 % (SDS-PAGE)
- niveau d'endotoxine
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product JAG2 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS + 0.02 % CHAPS.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Date de péremption
- 6 months
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- Antigène
- JAG2 (Jagged 2 (JAG2))
- Autre désignation
- Jagged-2 (JAG2 Produits)
- Synonymes
- D12Ggc2e Protein, Serh Protein, mJagged2-1 Protein, sm Protein, HJ2 Protein, SER2 Protein, jag2 Protein, serB Protein, zgc:152855 Protein, jagged 2 Protein, jagged 2b Protein, JAG2 Protein, jag2 Protein, Jag2 Protein, jag2b Protein
- Sujet
- Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
- Poids moléculaire
- ~150kDa (SDS-PAGE)
- UniProt
- Q9Y219
- Pathways
- Signalisation Notch, Sensory Perception of Sound
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