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JAG2 Protein (AA 1-1054) (Fc Tag)

JAG2 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS
N° du produit ABIN2745732
  • Antigène Voir toutes JAG2 Protéines
    JAG2 (Jagged 2 (JAG2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-1054
    Origine
    • 6
    • 4
    Humain
    Source
    • 6
    • 2
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette JAG2 protéine est marqué à la Fc Tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Humain
    Attributs du produit
    Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
    Pureté
    >90 % (SDS-PAGE)
    niveau d'endotoxine
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product JAG2 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 100 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS + 0.02 % CHAPS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Antigène
    JAG2 (Jagged 2 (JAG2))
    Autre désignation
    Jagged-2 (JAG2 Produits)
    Synonymes
    D12Ggc2e Protein, Serh Protein, mJagged2-1 Protein, sm Protein, HJ2 Protein, SER2 Protein, jag2 Protein, serB Protein, zgc:152855 Protein, jagged 2 Protein, jagged 2b Protein, JAG2 Protein, jag2 Protein, Jag2 Protein, jag2b Protein
    Sujet
    Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
    Poids moléculaire
    ~150kDa (SDS-PAGE)
    UniProt
    Q9Y219
    Pathways
    Signalisation Notch, Sensory Perception of Sound
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